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From Pitch to the Policy: Understanding the Morbidity & Mortality Impact of Chronic Traumatic Encephalopathy (CTE)

Chronic Traumatic Encephalopathy (CTE) is emerging as a complex, longtail mortality risk with implications that extend well beyond sports. Once viewed as a niche issue, it is now becoming increasingly relevant to life and health insurers, with potential impacts on underwriting and claims across multiple markets and products due to global litigation cases.

This article explores how repeated head impacts from concussion to sub concussive injury translate into evolving morbidity and mortality risk, why traditional underwriting frameworks may underestimate exposure, and what life insurers and reinsurers should consider as relevant medical evidence, diagnostics, and legal pressures continue to develop.

Why CTE Matters Now

CTE is a progressive neurodegenerative disease associated with repeated head impacts, including both concussive and sub-concussive injuries[1]. CTE can only be definitively confirmed post-mortem, while symptoms during life, often described under Traumatic Encephalopathy Syndrome (TES), overlap with depression, dementia, substance misuse, and other neurological or psychiatric disorders[2].

Concern for this disease has intensified as it has been diagnosed in athletes as young as 17 years old. In the two largest brain bank studies of contact-sport athletes, more than 80% of the brain donors who played American football, Canadian football, soccer, rugby and ice hockey were diagnosed with CTE. [3] Many professional and amateur athletes never even have a formal concussion recorded may experience repetitive head impacts over the course of a career.[4]

Another development is the issue of moving from medical debate into public, legal, and financial focus. High-profile litigation involving former players in rugby and football, together with the legacy of concussion-related settlements in American football[5], has increased scrutiny on what governing, sporting-bodies, and employers knew, or should have known, about long-term neurological risk.

For insurers, that combination of broader exposure, imperfect diagnosis, and rising legal awareness makes CTE relevant now not only as a medical issue, but as an underwriting, claims, and litigation challenge.

From Concussion to CTE

While most individuals recover fully from a concussion, repeated head injuries, particularly those sustained before complete recovery, may increase the risk of long-term neurological consequences.

Over time, it is the cumulative effect of repeated head impacts, rather than any single concussion, that is most relevant to Chronic Traumatic Encephalopathy (CTE). These symptoms may include mood and behavioral changes, cognitive impairment, and, in advanced cases, dementia.

From an insurance perspective, several characteristics of CTE are particularly significant:

  • Delayed onset – symptoms may not appear until long after an individual’s playing career or exposure has ended
  • Non-specific presentation – symptoms often overlap with mental health, neurological, and cognitive disorders
  • Uncertain causation – establishing a direct link between symptoms and prior head trauma can be challenging

How CTE Affects Mortality and Morbidity

CTE has implications for both mortality and morbidity risk, with effects that may emerge through overlapping cognitive, neurological, and behavioral pathways. For insurers, the challenge is not only the severity of potential outcomes, but also the delayed onset, non-specific presentation, and difficulty of diagnosing during life.

From a mortality perspective, concern centers on the association between CTE pathology and progressive cognitive decline, depression, and suicidality. While data continues to evolve, CTE introduces added complexity into mortality assessment, particularly where behavioral risk may emerge well beyond typical select periods and where prior exposure is not fully captured in the medical record.

For life insurers, this raises important considerations around:

  • Behavioral risk emerging beyond typical select periods
  • The interaction between neurological disease and suicide exclusions
  • The potential for under-recognized mortality drivers linked to past exposure

The implications of CTE are not limited to mortality. Its cognitive, psychiatric, and neurological manifestations may also create significant morbidity exposure, particularly where functional impairment develops gradually over time. Commonly observed symptoms include:

  • Impulsivity, aggression
  • Mood disorders
  • Cognitive decline
  • Depression and suicidality
  • Motor symptoms, including balance and coordination issues

These symptoms can have meaningful functional and psychosocial consequences, with potential impacts on personal and professional relationships, as well as social interaction.

Case Example

Consider a former amateur contact-sport athlete with a long playing history but no formally documented concussions. At underwriting, the available medical evidence may suggest standard or only moderately increased risk, because the true exposure profile is not fully visible in the record.

    • Exposure profile: Years of competitive play may include repeated sub-concussive impacts, minor head injuries, or on-field symptoms that were never medically assessed.
    • Later presentation: Years after leaving the sport, the individual develops gradual changes in memory, concentration, mood, and behavior.
    • Claims complexity: Symptoms may overlap with depression, early cognitive impairment, substance misuse, or other neurological disorders, making causation and classification difficult to establish.
    • Product impact: Functional decline could create morbidity exposure under disability, long-term care, or critical illness coverage, particularly where claims are submitted under dementia, traumatic brain injury, or cognitive impairment definitions.

Key takeaway: This scenario highlights the gap between recorded medical history and true cumulative exposure. For insurers, the challenge is that risk may be shaped by years of unrecorded impacts, while the eventual claim may present decades later through symptoms that are difficult to diagnose, attribute, and adjudicate with certainty.

Impacts & Underwriting Considerations

CTE highlights a broader challenge for insurers where traditional underwriting frameworks are often designed to assess discrete medical events rather than cumulative lifetime exposure. As understanding of repetitive head trauma continues to evolve, insurers may need to look beyond documented concussions and consider the totality of an individual’s exposure history.

Disclosure and Risk Assessment

Current applications typically focus on diagnosed conditions, treatment history, or prior concussions. However, many athletes experience numerous sub-concussive impacts that are never diagnosed or reported, making it difficult to fully assess exposure through traditional underwriting questions alone.

Evaluating Exposure

Risk may be influenced not only by whether an individual sustained a concussion, but also by factors such as years of participation, level of competition, position played, and cumulative head-impact exposure.

Product-Specific Implications

While CTE may ultimately contribute to mortality, i Cognitive decline, behavioral changes, and functional impairment can create significant exposure for critical illness, disability, and long-term care coverage.

Claims and Causation Challenges

The delayed onset and non-specific symptoms associated with CTE can complicate claims adjudication. As diagnostic criteria continue to evolve, questions surrounding causation, impairment, and coverage eligibility may become increasingly complex.

More broadly, CTE represents a shift from event-based risk assessment toward evaluating the long-term health consequences of cumulative exposure, a challenge that extends beyond professional athletes and may influence future underwriting approaches across multiple lines of business.

Conclusion

CTE is not a risk that can be addressed through simple exclusions or point-in-time underwriting questions. It reflects cumulative exposure over time, with impacts that may emerge long after exposure has ended.

For insurers and reinsurers, the focus is not on diagnosing CTE, but on better understanding how long-term neurological risk develops and how it may influence different product lines, particularly where morbidity exposure is more pronounced. As clinical understanding, diagnostics, and litigation continue to evolve, underwriting and claims frameworks will need to remain flexible as the definition and interpretation of risk continue to shift.

Contact Us

Please contact us if you would like to learn more about developments in neurological conditions such as CTE, or to discuss its mortality and morbidity implications. We would be happy to set up a meeting with you.

Contributor

Cillian Tierney, Head of Medical Underwriting Propositions & Products, Global Life & Health

This article is for general information, education and discussion purposes only and does not in any way constitute medical, legal or professional advice. 

References

[1] About Repeated Head Impacts | Traumatic Brain Injury & Concussion | CDC

[2] https://www.cdc.gov/traumatic-brain-injury/about/repeated-head-impacts.html

[3] https://concussionandcte.org/wp-content/uploads/2024/07/CTE-prevention-protocol-112023.pdf

[4] Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males | Nature Communications

[5] https://www.nflconcussionsettlement.com/FAQDetails.aspx?q=154

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